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1

IL-17 Signaling: The Yin and the Yang

Amatya, Nilesh, Garg, Abhishek V., Gaffen, Sarah L.

Journal:

Trends in Immunology

Year:

2017

Language:

english

File:

PDF, 3.00 MB

english, 2017

2

SY-13 Structure and function of the IL-17 receptor

Sarah L. Gaffen

Journal:

Year:

2008

Language:

english

File:

PDF, 121 KB

english, 2008

3

Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species

Whibley, Natasha, Gaffen, Sarah L.

Journal:

Year:

2015

Language:

english

File:

PDF, 846 KB

english, 2015

4

IL-17 receptor–based signaling and implications for disease

Li, Xiaoxia, Bechara, Rami, Zhao, Junjie, McGeachy, Mandy J., Gaffen, Sarah L.

Journal:

Nature Immunology

Year:

2019

Language:

english

File:

PDF, 1.45 MB

english, 2019

5

Host responses to Candida albicans: Th17 cells and mucosal candidiasis

Heather R. Conti, Sarah L. Gaffen

Journal:

Microbes and Infection

Year:

2010

Language:

english

File:

PDF, 323 KB

english, 2010

6

IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

Khader, Shabaana A, Bell, Guy K, Pearl, John E, Fountain, Jeffrey J, Rangel-Moreno, Javier, Cilley, Garth E, Shen, Fang, Eaton, Sheri M, Gaffen, Sarah L, Swain, Susan L

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 383 KB

english, 2007

7

Structure and signalling in the IL-17 receptor family

Gaffen, Sarah L.

Journal:

Nature Reviews Immunology

Year:

2009

Language:

english

File:

PDF, 530 KB

english, 2009

8

Structure–function relationships in the IL-17 receptor: Implications for signal transduction and therapy

Fang Shen, Sarah L. Gaffen

Journal:

Year:

2008

Language:

english

File:

PDF, 585 KB

english, 2008

9

The Interleukin (IL)‐2 Family Cytokines: Survival and Proliferation Signaling Pathways in T Lymphocytes

Benczik, Marta, Gaffen, Sarah L.

Journal:

Immunological Investigations

Year:

2004

Language:

english

File:

PDF, 673 KB

english, 2004

10

The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing

Gaffen, Sarah L., Jain, Renu, Garg, Abhishek V., Cua, Daniel J.

Journal:

Nature Reviews Immunology

Year:

2014

Language:

english

File:

PDF, 1.18 MB

english, 2014

11

Gut-Busters: IL-17 Ain’t Afraid of No IL-23

Whibley, Natasha, Gaffen, Sarah L.

Journal:

Year:

2015

Language:

english

File:

PDF, 513 KB

english, 2015

12

Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications

Monin, Leticia, Gaffen, Sarah L.

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2017

Language:

english

File:

PDF, 769 KB

english, 2017

13

Innate Immunity to Mucosal Candida Infections

Verma, Akash, Gaffen, Sarah, Swidergall, Marc

Journal:

Journal of Fungi

Year:

2017

Language:

english

File:

PDF, 626 KB

english, 2017

14

Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity

Gaffen, Sarah L., Moutsopoulos, Niki M.

Journal:

Science Immunology

Year:

2020

Language:

english

File:

PDF, 2.58 MB

english, 2020

15

A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss

Jaya Goswami, Nydiaris Hernández-Santos, Luis A. Zuniga, Sarah L. Gaffen

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 221 KB

english, 2009

16

CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model

Pushpa Pandiyan, Heather R. Conti, Lixin Zheng, Alanna C. Peterson, Douglas R. Mathern, Nydiaris Hernández-Santos, Mira Edgerton, Sarah L. Gaffen, Michael J. Lenardo

Journal:

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

17

JAK/STAT signaling by cytokine receptors

Kathleen D Liu, Sarah L Gaffen, Mark A Goldsmith

Journal:

Current Opinion in Immunology

Year:

1998

Language:

english

File:

PDF, 712 KB

english, 1998

18

IL-17RC: a partner in IL-17 signaling and beyond

Allen W. Ho, Sarah L. Gaffen

Journal:

Seminars in Immunopathology

Year:

2010

Language:

english

File:

PDF, 244 KB

english, 2010

19

The role of interleukin-17 in the pathogenesis of rheumatoid arthritis

Sarah L. Gaffen

Journal:

Current Rheumatology Reports

Year:

2009

Language:

english

File:

PDF, 321 KB

english, 2009

20

IL-17 signaling in host defense againstCandida albicans

Sarah L. Gaffen, Nydiaris Hernández-Santos, Alanna C. Peterson

Journal:

Immunologic Research

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

21

Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease

Reiko M. Onishi, Sarah L. Gaffen

Journal:

Year:

2010

Language:

english

File:

PDF, 751 KB

english, 2010

22

Structure and signalling in the IL-17 receptor family

Gaffen, Sarah L.

Journal:

Nature Reviews Immunology

Year:

2009

File:

PDF, 66 KB

2009

23

Is Monocyte Chemotactic Protein 1 Elevated in Aseptic Loosening of TKA?: A Pilot Study

Vinod Dasa MD, Jill M. Kramer DDS, PhD, Sarah L. Gaffen PhD, Keith L. Kirkwood DDS, PhD, William M. Mihalko MD, PhD

Journal:

Clinical Orthopaedics and Related Research®

Year:

2012

Language:

english

File:

PDF, 283 KB

english, 2012

24

Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation

Kathleen D. Liu, Sarah L. Gaffen, Mark A. Goldsmith, Warner C. Greene

Journal:

Current Biology

Year:

1997

Language:

english

File:

PDF, 162 KB

english, 1997

25

Interleukin-17: A New Paradigm in Inflammation, Autoimmunity, and Therapy

Kramer, Jill M., Gaffen, Sarah L.

Journal:

Journal of Periodontology

Year:

2007

Language:

english

File:

PDF, 3.87 MB

english, 2007

26

EXPRESSION OF THE IMMUNOGLOBULIN J CHAIN IN A MURINE B LYMPHOMA IS DRIVEN BY AUTOCRINE PRODUCTION OF INTERLEUKIN 2

Sarah L. Gaffen, Susan Wang, Marian E. Koshland

Journal:

Year:

1996

Language:

english

File:

PDF, 274 KB

english, 1996

27

SIGNALING DOMAINS OF THE INTERLEUKIN 2 RECEPTOR

Sarah L. Gaffen

Journal:

Year:

2001

Language:

english

File:

PDF, 1.65 MB

english, 2001

28

Th17 Cells in Immunity to Candida albicans

Nydiaris Hernández-Santos, Sarah L. Gaffen

Journal:

Cell Host & Microbe

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

29

Recent advances in the IL-17 cytokine family

Journal:

Current Opinion in Immunology

Year:

2011

Language:

english

File:

PDF, 505 KB

english, 2011

30

Overview of interleukin-2 function, production and clinical applications

Sarah L. Gaffen, Kathleen D. Liu

Journal:

Year:

2004

Language:

english

File:

PDF, 600 KB

english, 2004

31

78 Dissecting the IL-17 Receptor: Identification of a Pre-ligand Assembly Domain (PLAD) and Ligand Binding Site in IL-17RA

Jill M. Kramer, Walter Hanel, Fang Shen, Nilgun Isik, James P. Malone, Amarnath Maitra, Wade Sigurdson, David Swart, Joel Tocker, Tian Jin, Sarah L. Gaffen

Journal:

Year:

2007

Language:

english

File:

PDF, 50 KB

english, 2007

32

138 Distinct Functional Motifs Within the IL-17 Receptor Regulate Signal Transduction and Target Gene Expression

Fang Shen, Amarnath Maitra, Walter Hanel, Karen Mossman, Joel Tocker, David Swart, Sarah L. Gaffen

Journal:

Year:

2007

Language:

english

File:

PDF, 50 KB

english, 2007

33

52 Defining host T-cell responses in oral candidiasis

Heather R. Conti, Fang Shen, Namrata Nayyar, Eileen Stocum, Matthew J. Lindemann, Allen Ho, Patricia Masso-Welch, Mira Edgerton, Sarah L. Gaffen

Journal:

Year:

2008

Language:

english

File:

PDF, 49 KB

english, 2008

34

An overview of IL-17 function and signaling

Sarah L. Gaffen

Journal:

Year:

2008

Language:

english

File:

PDF, 387 KB

english, 2008

35

353 IL-17 signaling induces sequential phosphorylation of C/EBPβ

Fang Shen, Nan Li, Troy Wood, Sarah L. Gaffen

Journal:

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

36

Th17/IL-17 receptor signaling and not Th1 cells are essential for mucosal host defense against oral candidiasis

Sarah L. Gaffen, Heather R. Conti, Fang Shen, Namrata Nayyar, Eileen Stocum, Jianing Sun, Matthew J. Lindemann, Allen Ho, J. Hoda Hai, Patricia Masso-Welch

Journal:

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

37

SS2-4 Molecular and cellular contributions of IL-17RC to IL-17 signaling and host defense against fungal infections

Allen W. Ho, Fang Shen, Heather R. Conti, Nayan Patel, Alanna Peterson, Nydiaris Hernández-Santos, Jay K. Kolls, Lawrence Kane, Wenjun Ouyang, Erin E. Childs, Sarah L. Gaffen

Journal:

Year:

2010

Language:

english

File:

PDF, 147 KB

english, 2010

38

CS6-1 A SEFIR is not enough: Structure and function in the IL-17 receptor superfamily

Sarah L. Gaffen, Reiko M. Onishi, Sangmi J. Park, Allen W. Ho, Amarnath Maitra, Walter Hanel, Fang Shen

Journal:

Year:

2010

Language:

english

File:

PDF, 130 KB

english, 2010

39

PS2-29 IL-17 and its Jekyll-and-Hyde role in the regulation of fat and bone

Mushtaq Ahmed, Jaya Goswami, Nydiaris Hernández-Santos, Sarah L. Gaffen

Journal:

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

40

PS1-037. Cellular mediators of long-term protective immunity to Candida albicans in oropharyngeal candidiasis

Nydiaris Hernandez-Santos, Alanna C. Peterson, Sarah Gaffen

Journal:

Year:

2011

Language:

english

File:

PDF, 40 KB

english, 2011

41

CS11-2. Signaling by the IL-17RA/IL-17RC Complex: Impact on oral mucosal immunity

Sarah Gaffen, Allen W Ho, Reiko Onishi, Fang Shen, Alanna Peterson, Nydiaris Hernández-Santos, Abhishek Garg, Wenjun Ouyang, Erin E Childs

Journal:

Year:

2011

Language:

english

File:

PDF, 130 KB

english, 2011

42

IL-17 in obesity and adipogenesis

Mushtaq Ahmed, Sarah L. Gaffen

Journal:

Cytokine & Growth Factor Reviews

Year:

2010

Language:

english

File:

PDF, 194 KB

english, 2010

43

Biology of recently discovered cytokines: Interleukin-17 – a unique inflammatory cytokine with roles in bone biology and arthritis

Journal:

Arthritis Research & Therapy

Year:

2004

Language:

english

File:

PDF, 342 KB

english, 2004

44

IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors

Ahmed, Mushtaq, Gaffen, Sarah L.

Journal:

Year:

2013

Language:

english

File:

PDF, 660 KB

english, 2013

45

124

Huppler, Anna R., Hernández-Santos, Nydiaris, Conti, Heather R., Gaffen, Sarah L.

Journal:

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

46

279

Whibley, Natasha, Mamo, Anna J., Traggiai, Elisabetta, Kolbinger, Frank, Vogel, Beate, Kammüller, Michael, Siebenlist, Ulrich, Gaffen, Sarah L.

Journal:

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

47

236

Sheehan, Robert P., Garg, Abhishek, Gaffen, Sarah L., Faeder, James R.

Journal:

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

48

The Molecular Role of the Common γcSubunit in Signal Transduction Reveals Functional Asymmetry within Multimeric Cytokine Receptor Complexes

Stephen Y. Lai, Weiduan Xu, Sarah L. Gaffen, Kathleen D. Liu, Gregory D. Longmore, Warner C. Greene and Mark A. Goldsmith

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 489 KB

english, 1996

49

Rheumatoid arthritis patients exhibit impairedCandida albicans-specific Th17 responses

Bishu, Shrinivas, Su, Ee, Wilkerson, Erich R, Reckley, Kelly A, Jones, Donald M, McGeachy, Mandy J, Gaffen, Sarah L, Levesque, Marc C

Journal:

Arthritis Research & Therapy

Year:

2014

Language:

english

File:

PDF, 268 KB

english, 2014

50

Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy

Anna R Huppler,Shrinivas Bishu,Sarah L Gaffen

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 268 KB

english, 2012